Serum and Urine Selenium Concentrations in Patients with Cardiovascular Diseases and Relationship to Other Nutritional Indexes
Miguel Navarro-Alarcóna, Herminia López-Garcia de la Serranaa, Vidal Pérez-Valerob, Carmen López-MartÃneza
aDepartment of Nutrition and Bromatology, Faculty of Pharmacy, University of Granada, and bLaboratory of Clinical Analyses, Motril Hospital, Motril, Granada, Spain
Mean serum Se concentrations measured in patients with acute myocardial infarction (AMI; n = 32) or with ischemic cardiomyopathy (n = 50) were significantly lower than those determined in control groups. In AMI patients, serum triglyceride levels showed a positive significant correlation with the serum Se concentration (r = 0.59, p < 0.05).
This result reinforces the important role of Se as an antioxidant agent in this disease. Mean urine Se concentrations of AMI patients (n = 33) were also significantly lower to those determined in the control group (p < 0.05). This reaction of the organism contributes to regulate the Se homeostasis to keep the body Se status as high as possible.
